The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2017

Filed:

Mar. 22, 2013
Applicants:

Laboratorios Del Dr. Esteve S.a., Barcelona, ES;

Fundació Privada Institut DE Recerca DE LA Sida—caixa, Badalona, ES;

Institució Catalana DE Recerca I Estudis Avançats, Barcelona, ES;

Inventors:

Marta Ruiz Riol, Badalona, ES;

Christian Brander, Tiana, ES;

Javier Ibarrondo, Culver City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); G01N 33/50 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6866 (2013.01); G01N 33/505 (2013.01); G01N 33/5091 (2013.01); G01N 33/56988 (2013.01); G01N 2333/15 (2013.01); G01N 2333/52 (2013.01); G01N 2333/525 (2013.01); G01N 2333/54 (2013.01); G01N 2333/555 (2013.01); G01N 2800/52 (2013.01); G01N 2800/56 (2013.01); G01N 2800/60 (2013.01);
Abstract

The invention relates to a method and a diagnostic kit for monitoring HIV specific T cell responses and identifying subjects capable of controlling HIV progression or preventing HIV infection altogether. The method is based on the combined use of boosted flow cytometry and toggle peptides and can cover a large set of effector functions. The method is also suitable to detect T cell responses of any desirable cytokine or combination of cytokines to any pathogen.


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