The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2017

Filed:

Jan. 28, 2016
Applicant:

Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Akila Jayaraman, Waltham, MA (US);

Karthik Viswanathan, Waltham, MA (US);

Rahul Raman, Waltham, MA (US);

Zachary H. Shriver, Cambridge, MA (US);

Ram Sasisekharan, Lexington, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
G01N 33/56983 (2013.01); C07K 14/005 (2013.01); C12N 2760/16122 (2013.01); G01N 2333/11 (2013.01); G01N 2800/50 (2013.01);
Abstract

The present invention provides HA polypeptides (e.g., H1 HA polypeptides) that bind to umbrella-topology glycans, and reagents and methods relating thereto. The present invention provides binding agents that bind to HA polypeptides (e.g., H1 HA polypeptides), and reagents and methods relating thereto. The present invention provides interfering agents that inhibit the binding of HA polypeptides (e.g., H1 HA polypeptides) to HA receptors, and reagents and methods relating thereto. The present invention provides compositions and methods for treating, preventing, and/or diagnosing influenza infection utilizing HA polypeptides, HA polypeptide binding agents, HA polypeptide interfering agents, and/or vaccine compositions comprising any of the foregoing.


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