The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2017
Filed:
Jul. 29, 2011
Khalid S. Salaita, Decatur, GA (US);
Pradeep M. Nair, San Francisco, CA (US);
Joe W. Gray, Lake Osewego, OR (US);
John T. Groves, Berkeley, CA (US);
Khalid S. Salaita, Decatur, GA (US);
Pradeep M. Nair, San Francisco, CA (US);
Debopriya Das, Albany, CA (US);
Joe W. Gray, Lake Osewego, OR (US);
John T. Groves, Berkeley, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
A signature of a condition of a live cell is established in an assay that allows distribution of the receptors on the cell surface in response to binding a ligand. The receptors can be optically detected and quantified to provide a value for the condition, Test drugs can be screened for therapeutic potential in the assay: a potentially efficacious drug is identified by an ability to modulate an established signature. The receptor distribution signature can be corroborated with an mRNA expression profile of several genes, indicating, for example, metastasis.