The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2017

Filed:

Jul. 06, 2015
Applicant:

National Taiwan University of Science and Technology, Taipei, TW;

Inventors:

Chang-Mou Wu, Taipei, TW;

Hsiu-An Yu, Taipei, TW;

Chun-Chung Huang, Taipei, TW;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/54 (2006.01); C12N 9/04 (2006.01); C12Q 1/00 (2006.01); G01N 27/327 (2006.01); B82Y 15/00 (2011.01);
U.S. Cl.
CPC ...
C12Q 1/54 (2013.01); C12N 9/0006 (2013.01); C12Q 1/004 (2013.01); C12Q 1/006 (2013.01); G01N 27/3272 (2013.01); G01N 27/3278 (2013.01); B82Y 15/00 (2013.01); C12Y 101/03004 (2013.01);
Abstract

An electrospun nanofibrous membrane is sheet like and is formed by multiple glucose oxidase/potassium hexacyanoferrate(III) modified electrospun nanofibers. The glucose oxidase/potassium hexacyanoferrate(III) modified electrospun nanofibers are PVA electrospun nanofibers containing glucose oxidase and potassium hexacyanoferrate(III) homogeneously dispersed therein. The glucose oxidase/potassium hexacyanoferrate(III) modified electrospun nanofibers are PVA electrospun nanofibers and are cross-linked by glutaraldehyde vapor with ultrasonic energy assistance. Graphene modified PVA/GOx electrospun membranes were prepared to examine the immobilization mechanism between graphene and GOx. The electrochemical measurement results show that the sensitivities increased with increasing graphene concentrations up to 20 ppm. The highest sensitivity recorded 38.7 μA/mM was for a PVA/GOx membrane with 20 ppm graphene representing a 109% increase over a membrane made without graphene.


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