The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2017
Filed:
Jul. 15, 2016
Applicant:
Commonwealth Scientific and Industrial Research Organisation, Acton ACT, AU;
Inventors:
Peter Michael Waterhouse, Paddington, AU;
Ming-Bo Wang, Kaleen, AU;
Assignee:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/82 (2006.01); C12N 9/24 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8218 (2013.01); C12N 9/2405 (2013.01); C12N 15/8216 (2013.01); C12N 15/8247 (2013.01); C12N 15/8283 (2013.01); C12Y 302/01031 (2013.01);
Abstract
Methods and means are provided for reducing the phenotypic expression of a nucleic acid of interest in eukaryotic cells by providing aberrant, preferably unpolyadenylated, target-specific RNA to the nucleus of the host cell. Preferably, the unpolyadenylated, target-specific RNA is provided by transcription of a chimeric gene comprising a promoter and a DNA region encoding the target-specific RNA.