The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2017
Filed:
Apr. 22, 2014
Applicants:
Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;
Universite Paris Descartes, Paris, FR;
Inventors:
Roberto Mallone, Paris, FR;
Georgia Afonso, Paris, FR;
Assignees:
INSERM (Institut National de la Sante et de la Recherche Medicale), Paris, FR;
Universite Paris Descartes, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); C07K 14/545 (2006.01); C12N 5/0783 (2010.01); G01N 33/50 (2006.01); G01N 33/564 (2006.01); G01N 33/569 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 38/2006 (2013.01); C07K 14/545 (2013.01); G01N 33/505 (2013.01); G01N 33/564 (2013.01); G01N 33/569 (2013.01); G01N 33/56972 (2013.01); G01N 33/574 (2013.01); C12N 2501/115 (2013.01); C12N 2501/22 (2013.01); C12N 2501/2301 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2304 (2013.01); C12N 2501/2307 (2013.01); C12N 2501/25 (2013.01); C12N 2501/26 (2013.01); C12N 2501/999 (2013.01); G01N 2333/57 (2013.01); G01N 2333/70514 (2013.01); G01N 2333/70517 (2013.01); G01N 2469/10 (2013.01); G01N 2500/10 (2013.01);
Abstract
The present invention relates to methods for stimulating antigen-specific T cell responses. In particular, the invention relates to a method for stimulating antigen (Ag)-specific T cell responses in a blood sample or PBMC sample isolated from a subject comprising the step consisting in culturing said blood or PBMC sample in a appropriate culture medium which comprises an amount of IL-1beta and an amount of a least one antigen.