The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2017

Filed:

Sep. 28, 2012
Applicant:

Korea Advanced Institute of Science and Technology, Daejeon, KR;

Inventors:

Won Do Heo, Daejeon, KR;

Sang Kyu Lee, Seoul, KR;

Hye Rim Park, Gimhae-si, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C07K 14/47 (2006.01); C07K 14/325 (2006.01); C07K 14/415 (2006.01); C12N 9/00 (2006.01); C12N 9/12 (2006.01); C12N 13/00 (2006.01); G01N 33/58 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4728 (2013.01); C07K 14/325 (2013.01); C07K 14/415 (2013.01); C12N 9/12 (2013.01); C12N 9/93 (2013.01); C12N 13/00 (2013.01); C12Y 207/11017 (2013.01); G01N 33/582 (2013.01); G01N 33/6845 (2013.01); C07K 2319/60 (2013.01); C07K 2319/735 (2013.01);
Abstract

To efficiently analyze interaction and function between proteins, the present invention relates to a method for forming a light-induced protein nanocluster, comprising: an expression vector preparation step of preparing a first expression vector including polynucleotides coding a first fusion protein including a light-induced heterodimer-forming protein and a first self-assembly protein, and a second expression vector including polynucleotides coding a couple protein that forms a homodimer with said light-induced heterodimer-forming protein, or a second fusion protein including said couple protein and a second self-assembly protein; a transformed cell, tissue or individual preparation step of transforming cells, tissues or individuals using said first expression vector and second expression vector; and a light radiation step of radiating light having a wavelength for inducing the formation of heterodimer between said light-induced heterodimer-forming protein and said couple protein, to said transformed cells, tissue or individuals.


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