The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2017
Filed:
Oct. 28, 2013
Monash University, Victoria, AU;
Peptides International, Inc., Louisville, KY (US);
Baylor College of Medicine, Houston, TX (US);
Raymond S. Norton, Victoria, AU;
Serdar Kuyucak, New South Wales, AU;
M Harunur Rashid, New South Wales, AU;
Michael Pennington, Shelbyville, KY (US);
Christine Beeton, Pearland, TX (US);
Monash University, Victoria, AU;
Baylor College of Medicine, Houston, TX (US);
Peptides International, Inc., Louisville, KY (US);
Abstract
A novel peptide analogue of thetoxin HsTX1 is disclosed along with its application as, for example, a therapeutic agent for treating an autoimmune disease such as multiple sclerosis (MS) or rheumatoid arthritis (RA). The analogue comprises a peptide with an amino acid substitution at amino acid position 14 of the wild-type (WT) peptide sequence (or a position corresponding to position 14 of the WT peptide sequence). The analogue exhibits selectivity for Kv1.3 over Kv1.1 and other potassium channels relative to the WT peptide.