The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2017

Filed:

Aug. 17, 2012
Applicants:

Marco Kessler, Danvers, MA (US);

Angelika Fretzen, Somerville, MA (US);

Hong Zhao, Lexington, MA (US);

Robert Solinga, Brookline, MA (US);

Vladimir Volchenok, Waltham, MA (US);

Inventors:

Marco Kessler, Danvers, MA (US);

Angelika Fretzen, Somerville, MA (US);

Hong Zhao, Lexington, MA (US);

Robert Solinga, Brookline, MA (US);

Vladimir Volchenok, Waltham, MA (US);

Assignee:

Ironwood Pharmaceuticals, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C11D 3/34 (2006.01); C07K 7/54 (2006.01); C07K 5/02 (2006.01); A61K 38/10 (2006.01); A61K 38/12 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61K 38/10 (2013.01); A61K 38/12 (2013.01); A61K 45/06 (2013.01); C07K 5/02 (2013.01); C07K 7/54 (2013.01); C11D 3/3436 (2013.01); G01N 2800/065 (2013.01);
Abstract

The present invention features peptides, compositions, and related methods for treating gastrointestinal disorders and conditions, including but not limited to, irritable bowel syndrome (IBS), gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia, visceral pain, gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudo-obstruction), disorders and conditions associated with constipation, and other conditions and disorders are described herein, using peptides and other agents that activate the guanylate cyclase C (GC-C) receptor.


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