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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9708316 B1

PDFFull Text
Date of Patent:
Jul. 18, 2017

Filed:

Dec. 22, 2015

Tgfβr antagonists

Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Brian E. Fink, Yardley, PA (US);

Yufen Zhao, Pennington, NJ (US);

Robert M. Borzilleri, New Hope, PA (US);

Liping Zhang, East Windsor, NJ (US);

Kyoung S. Kim, Vancouver, WA (US);

Muthoni G. Kamau, Lawrenceville, NJ (US);

Andrew J. Tebben, New Hope, PA (US);

Yong Zhang, West Windsor, NJ (US);

Andrew F. Donnell, West Windsor, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:

Elliott Korsen

Primary Examiner:

Noble Jarrell

Assistant Examiner:

Daniel Carcanague

Int. Cl.
CPC ...
A61K 31/4709 (2006.01); A61K 31/501 (2006.01); C07D 487/04 (2006.01); C07D 471/04 (2006.01); A61K 31/5377 (2006.01); A61K 31/437 (2006.01); A61K 31/496 (2006.01); A61K 31/4985 (2006.01); A61K 31/506 (2006.01); A61K 31/541 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61K 31/4709 (2013.01); A61K 31/496 (2013.01); A61K 31/4985 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); C07D 487/04 (2013.01);
Abstract

The invention relates generally to compounds that modulate the activity of TGFβR-1 and TGFβR-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

Find Patent Forward Citations

Fink, Brian. (2017). Tgfβr antagonists (U.S. Patent No. 9708316). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9708316

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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