The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2017
Filed:
Mar. 18, 2015
Wuhan Ll Science and Technology Development Co., Ltd, Wuhan, Hubei, CN;
Wuhan Qr Pharmaceuticals Co., Ltd, Wuhan, Hubei, CN;
Jian Ge, Hubei, CN;
Jianyi Ma, Hubei, CN;
Guangya Xiang, Hubei, CN;
Wei Wang, Hubei, CN;
Chaodong Wang, Hubei, CN;
WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD, Wuhan, Hubei, CN;
WUHAN QR PHARMACEUTICALS CO., LTD, Wuhan, Hubei, CN;
Abstract
The invention belongs to the technical field of pharmaceutical chemistry, and particularly pertains to benzimidazole derivatives, and preparation process and pharmaceutical uses thereof. Benzimidazole derivatives include Ligustrazine and NO donor derivatives. The kind of the compounds can rapidly release Ligustrazine or No in vivo, so that they can produce effective synergetic effects with Azilsartan, to enhance the anti-hypertension effect, and reduce adverse effects, and the released Ligustrazine can produce ideal protection to patients' livers and kidneys, thereby filling blanks in the prior art.