The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2017
Filed:
Aug. 01, 2014
Université Laval, Québec, CA;
Donald Poirier, L'Ancienne Lorette, CA;
René Maltais, Québec, CA;
UNIVERSITÉ LAVAL, Québec, CA;
Abstract
Provided are compounds of general formula A and A', wherein Xand Xare each C, CH or N; Rand Rare each H, optionally substituted C-Csaturated or unsaturated chemical group, or together form an optionally substituted C-Ccycle; Z; Zand Zare each N or CH; V is C═O, C═S or CH; n is from 1 to 12; Wand Ware each H, CH, O or S; and Rand Rare each H, CrCalkyl, CCaryl, CCalkylaryl, optionally substituted phenyl, CCalkoxy, CCthioalkoxy, F, Cl, Br or I. These compounds inhibit steroid sulfatase (STS), act as selective estrogen receptor modulators (SERMs), increase alkaline phosphatase (ALP) activity, and are useful in the treatment of medical conditions involving hormones such as breast cancer, prostate cancer, endometriosis, osteoporosis, benign prostatic hyperplasia and endometrial cancer.