The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2017
Filed:
May. 10, 2016
Applicant:
Takeda Pharmaceutical Company Limited, San Diego, CA (US);
Inventors:
Jason W. Brown, San Diego, CA (US);
Melinda Davis, San Diego, CA (US);
Anthony Ivetac, San Diego, CA (US);
Benjamin Jones, Cardiff-by-the-Sea, CA (US);
Andre A. Kiryanov, San Diego, CA (US);
Jon Kuehler, San Diego, CA (US);
Marion Lanier, San Diego, CA (US);
Joanne Miura, San Diego, CA (US);
Sean Murphy, San Diego, CA (US);
Xiaolun Wang, San Diego, CA (US);
Assignee:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); A61K 31/443 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/5377 (2006.01); A61K 31/496 (2006.01); A61K 31/551 (2006.01); C07D 401/04 (2006.01); C07D 491/107 (2006.01); C07D 417/14 (2006.01); C07D 471/08 (2006.01); C07D 487/06 (2006.01); C07D 487/10 (2006.01); C07D 491/10 (2006.01); A61K 31/4545 (2006.01); A61K 31/4985 (2006.01); A61K 31/5513 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/444 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); A61K 31/4985 (2013.01); A61K 31/5377 (2013.01); A61K 31/551 (2013.01); A61K 31/5513 (2013.01); C07D 401/04 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/08 (2013.01); C07D 487/04 (2013.01); C07D 487/06 (2013.01); C07D 487/10 (2013.01); C07D 491/10 (2013.01); C07D 491/107 (2013.01);
Abstract
The present invention provides compounds of the formula: which are useful as inhibitors of PHD, pharmaceutical compositions thereof, methods for treatment of conditions associated with HIF, processes for making the compounds and intermediates thereof.