The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2017

Filed:

May. 09, 2016
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Thomas David McCarthy, Old Greenwich, CT (US);

Alan Naylor, Royston, GB;

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 241/04 (2006.01); C07D 403/04 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); C07D 413/04 (2006.01); C07D 413/06 (2006.01); C07D 243/08 (2006.01); C07D 231/12 (2006.01); C07D 295/185 (2006.01);
U.S. Cl.
CPC ...
C07D 241/04 (2013.01); C07D 231/12 (2013.01); C07D 243/08 (2013.01); C07D 295/185 (2013.01); C07D 403/04 (2013.01); C07D 413/04 (2013.01); C07D 413/06 (2013.01);
Abstract

The present invention relates to heterocyclic compounds useful for antagonizing angiotensin II Type 2 (AT) receptor. More particularly the invention relates to piperazine and diazepine compounds, compositions containing them and their use in methods of treating or preventing disorders or diseases associated with ATreceptor function including neuropathic pain, inflammatory pain, conditions associated with neuronal hypersensitivity, impaired nerve conduction velocity, cell proliferation disorders, disorders associated with an imbalance between bone resorption and bone formation and disorders associated with aberrant nerve regeneration.


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