The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2017
Filed:
Aug. 28, 2015
Applicant:
Tes Pharma S.r.l., Corciano, IT;
Inventors:
Assignee:
TES Pharma S.r.l., , IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/38 (2006.01); C07D 403/12 (2006.01); C07D 233/68 (2006.01); C07D 233/84 (2006.01); C07D 233/96 (2006.01); C07D 407/12 (2006.01); C07D 409/12 (2006.01); A61K 31/505 (2006.01); A61K 31/513 (2006.01); C07D 239/56 (2006.01); C07D 401/04 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/04 (2006.01);
U.S. Cl.
CPC ...
C07D 239/38 (2013.01); A61K 31/505 (2013.01); A61K 31/513 (2013.01); C07D 233/68 (2013.01); C07D 233/84 (2013.01); C07D 233/96 (2013.01); C07D 239/56 (2013.01); C07D 401/04 (2013.01); C07D 403/12 (2013.01); C07D 405/04 (2013.01); C07D 407/12 (2013.01); C07D 409/04 (2013.01); C07D 409/12 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/04 (2013.01);
Abstract
The present disclosure discloses compounds capable of modulating the activity of α-amino-β-carboxymuconic acid semialdehyde decarboxylase (ACMSD), which are useful for the prevention and/or the treatment of diseases and disorders associated with defects in NADbiosynthesis, e.g., metabolic disorders, neurodegenerative diseases, chronic inflammatory diseases, kidney diseases, and diseases associated with ageing. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament.