The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 18, 2017

Filed:

Mar. 10, 2015
Applicants:

International Aids Vaccine Initiative, New York, NY (US);

The Scripps Research Institute, La Jolla, CA (US);

Inventors:

William R. Schief, New York, NY (US);

Bruno E. Correia, La Jolla, CA (US);

Daniel W. Kulp, New York, NY (US);

Ron Jacak, New York, NY (US);

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01); C07K 16/10 (2006.01); C12N 7/00 (2006.01); C12Q 1/68 (2006.01); A61K 39/00 (2006.01); A61K 39/12 (2006.01);
U.S. Cl.
CPC ...
A61K 39/21 (2013.01); A61K 39/12 (2013.01); C12N 7/00 (2013.01); A61K 2039/64 (2013.01); C12N 2740/16034 (2013.01);
Abstract

The present application relates to immunogens of broadly neutralizing monoclonal antibodies specific for HIV-1, such as broad and potent neutralizing monoclonal antibodies specific for HIV-1 and their gernation and methods of use. Broad neutralization suggests that the antibodies can neutralize HIV-1 isolates from different individuals. Immunogens or vaccines which may elicit such antibody associated responses are useful in pharmaceutical compositions for the prevention and treatment of HIV, and for the diagnosis and monitoring of HIV infection.


Find Patent Forward Citations

Loading…