The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 18, 2017
Filed:
Jul. 09, 2014
Applicant:
Northwestern University, Evanston, IL (US);
Inventors:
Melina R. Kibbe, Chicago, IL (US);
Guillermo A. Ameer, Chicago, IL (US);
Vinit N. Varu, Chicago, IL (US);
Assignee:
Northwestern University, Evanston, IL (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61K 38/49 (2006.01); A61K 38/54 (2006.01); A61M 37/00 (2006.01); A61B 17/22 (2006.01); A61K 31/724 (2006.01); A61K 45/06 (2006.01); A61M 25/10 (2013.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/4886 (2013.01); A61B 17/2202 (2013.01); A61K 31/724 (2013.01); A61K 38/49 (2013.01); A61K 38/54 (2013.01); A61K 45/06 (2013.01); A61M 25/1011 (2013.01); A61M 37/0092 (2013.01); C12Y 304/21068 (2013.01); C12Y 304/24003 (2013.01); C12Y 304/24024 (2013.01); C12Y 304/24035 (2013.01); A61K 9/0019 (2013.01);
Abstract
Disclosed are pharmaceutical compositions and methods for digesting atherosclerotic plaques in a patient in need thereof. The compositions include and the methods utilize a mixture of collagenases for digesting plaques and optionally may include or utilize additional agents such as cyclodextrins, chelating agents, and tissue plasminogen activator.