The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2017

Filed:

Aug. 08, 2012
Applicants:

Luis Barneo Serra, Derio-Vizcaya, ES;

Carmen Garcia Pravia, Derio-Vizcaya, ES;

Juan Ramon DE Los Toyos Gonzalez, Derio-Vizcaya, ES;

Marcos Garcia Ocana, Derio-Vizcaya, ES;

Jose Fernando Vazquez Villa, Derio-Vizcaya, ES;

Nelson Fuentes Martinez, Derio-Vizcaya, ES;

Jokin Del Amo Iribarren, Derio-Vizcaya, ES;

Laureano Simon Buela, Derio-Vizcaya, ES;

Inventors:

Luis Barneo Serra, Derio-Vizcaya, ES;

Carmen Garcia Pravia, Derio-Vizcaya, ES;

Juan Ramon De Los Toyos Gonzalez, Derio-Vizcaya, ES;

Marcos Garcia Ocana, Derio-Vizcaya, ES;

Jose Fernando Vazquez Villa, Derio-Vizcaya, ES;

Nelson Fuentes Martinez, Derio-Vizcaya, ES;

Jokin Del Amo Iribarren, Derio-Vizcaya, ES;

Laureano Simon Buela, Derio-Vizcaya, ES;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); G01N 33/574 (2006.01); C07K 16/18 (2006.01); C07K 16/30 (2006.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57484 (2013.01); C07K 16/18 (2013.01); C07K 16/30 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5011 (2013.01); G01N 33/6881 (2013.01); G01N 33/6887 (2013.01); C07K 2317/33 (2013.01); C12Q 2600/118 (2013.01); G01N 2333/78 (2013.01); G01N 2800/56 (2013.01);
Abstract

The present invention relates to in vitro methods and products for detecting the presence of an invasive carcinoma in an individual, for determining and/or predicting the stage and/or invasiveness of said carcinoma in an individual, or for monitoring the effect of the therapy administered to an individual who has said carcinoma based on col11a1 gene and proCOL11A1 protein expression. The invention also relates to the search for, identification, development and evaluation of the efficacy of compounds for therapy for said carcinoma, for the purpose of developing new medicinal products. The invention also relates to agents inhibiting proCOL11A1 protein expression and/or activity, and/or the effects of this expression.


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