The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2017
Filed:
May. 30, 2013
Jw Creagene Inc., Seongnam-si, Gyeonggi-do, KR;
Yoon Lee, Yongin-si, KR;
Hye-Won Kang, Seongnam-si, KR;
Seung-Soo Han, Gwangju-si, KR;
Young-Mok Kim, Seoul, KR;
Yong-Soo Bae, Suwon-si, KR;
Seo-Hee Ahn, Gwangju-si, KR;
JW CREAGENE INC., Seongnam-si, KR;
Abstract
The present invention relates to a composition for maturing dendritic cells, comprising, as a maturation-promoting factor, Interleukin-1β (IL-1β), Interleukin-6 (IL-6), Tumor necrosis factor-α (TNF-α), Interferon-γ (IFN-γ), Prostaglandin E2 (PGE2), Picibanil (OK432) and/or Poly IC. The composition for maturing dendritic cells of the present invention may have the effects of not only improving the ability of dendritic cells to induce an immune response, but also of decreasing the antigen non-specific immune response of dendritic cells and increasing antigen-specific immune response of dendritic cells, thus maximizing the effects of immunotherapy.