The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2017
Filed:
May. 23, 2014
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Laurence J N Cooper, Houston, TX (US);
Bipulendu Jena, Houston, TX (US);
Sourindra Maiti, Houston, TX (US);
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/42 (2006.01); C07K 16/28 (2006.01); C12N 5/0783 (2010.01); C07K 14/705 (2006.01); G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
C07K 16/4208 (2013.01); C07K 14/70503 (2013.01); C07K 14/70517 (2013.01); C07K 16/2803 (2013.01); C07K 16/4283 (2013.01); C12N 5/0636 (2013.01); G01N 33/566 (2013.01); C07K 2317/622 (2013.01); C07K 2317/74 (2013.01); C07K 2317/75 (2013.01); C07K 2317/76 (2013.01); C07K 2319/02 (2013.01); C07K 2319/31 (2013.01); C07K 2319/33 (2013.01); C12N 2510/00 (2013.01);
Abstract
Provided are monoclonal antibodies that detect CD 19 CAR-modified immune cells and CAR-modified immune cells irrespective of the tumor associated antigen they target. Methods of using these functional monoclonal antibodies include, but are not limited to, detection, quantification, activation, and selective propagation of CAR-modified immune cells.