The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2017
Filed:
Aug. 19, 2011
Shuji Sato, Narita, JP;
Takeshi Goto, Ushiku, JP;
Shigeru Goto, Beppu, TW;
Toshiaki Nakano, Kaohsiung, TW;
Naoya Ohmori, Chiba, JP;
Kueichen Chiang, Tokyo-to, JP;
Yayoi Shimada, Kisarazu, JP;
Kenji Mori, Ryugasaki, JP;
Takamitsu Miyagi, Sodegaura, JP;
Shuji Sato, Narita, JP;
Takeshi Goto, Ushiku, JP;
Shigeru Goto, Beppu, TW;
Toshiaki Nakano, Kaohsiung, TW;
Naoya Ohmori, Chiba, JP;
Kueichen Chiang, Tokyo-to, JP;
Yayoi Shimada, Kisarazu, JP;
Kenji Mori, Ryugasaki, JP;
Takamitsu Miyagi, Sodegaura, JP;
Josai University Corporation, Tokyo-to, JP;
Abstract
The present invention relates to a monoclonal antibody having excellent immunosuppressive activity or an antigen binding fragment thereof. More specifically, the present invention relates to a monoclonal antibody or an antigen binding fragment thereof, which binds to a peptide consisting an amino acid sequence represented by SSVLYGGPPSAA (SEQ ID NO: 1) or a conjugate of the peptide and a pharmaceutically acceptable carrier, the monoclonal antibody or an antigen binding fragment thereof having a higher binding affinity for core histone than for histone H1.