The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2017
Filed:
Sep. 26, 2013
Applicant:
Research Development Foundation, Carson City, NV (US);
Inventors:
Dennis T. Brown, Raleigh, NC (US);
Raquel Hernandez, Raleigh, NC (US);
Assignee:
Research Development Foundation, Carson City, NV (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); A61K 38/00 (2006.01); C07K 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 38/00 (2013.01); C07K 7/00 (2013.01); C12N 2770/36122 (2013.01); C12N 2770/36134 (2013.01);
Abstract
Novel attenuating deletions of Chikungunya virus E2 polypeptides are provided as are attenuated viruses comprising the deletions. Also provided are immunogenic compositions comprising the attenuated viruses and methods of producing such viruses in cells (such as insect cells). Viruses of the embodiments can be used for immunization of animals to provide protection from the pathogenic effects of Chikungunya virus infection.