The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2017
Filed:
Oct. 07, 2015
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Mark Strohmeier, Arlington, MA (US);
John Caesar, Jr., Lancaster, MA (US);
Patrick Raymond Connelly, Harvard, MA (US);
Majed Fawaz, Foxboro, MA (US);
Eduard Luss-Lusis, Belmont, MA (US);
Brian McClain, Harvard, MA (US);
Ales Medek, Winchester, MA (US);
Hai Miao, Winchester, MA (US);
Kwame Wiredu Nti-Addae, Tewksbury, MA (US);
Ping Yin, Arlington, MA (US);
Yuegang Zhang, Wayland, MA (US);
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Abstract
The present disclosure relates to co-crystals comprising N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and a co-former and methods for their preparation. The present disclosure further relates to pharmaceutical compositions comprising the co-crystal forms, as well as methods of treatment therewith and kits.