The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2017

Filed:

Dec. 30, 2013
Applicant:

South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou, Guangdong, CN;

Inventors:

Xianwen Yang, Guangzhou, CN;

Kun Peng, Guangzhou, CN;

Sumei Li, Guangzhou, CN;

Gaiyun Zhang, Guangzhou, CN;

Jie Li, Guangzhou, CN;

Xiuping Lin, Guangzhou, CN;

Yonghong Liu, Guangzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 35/37 (2006.01); C12P 7/02 (2006.01); C12R 1/465 (2006.01); C12P 5/00 (2006.01); C12P 15/00 (2006.01);
U.S. Cl.
CPC ...
C07C 35/37 (2013.01); C12P 5/007 (2013.01); C12P 7/02 (2013.01); C12P 15/00 (2013.01); C12R 1/465 (2013.01); C07C 2103/97 (2013.01);
Abstract

The invention discloses a new strepsesquitriol A, a preparation method thereof and an application thereof. Strepsesquitriol A, a structure as shown in Formula (I), is a compound having a new skeleton and strongly inhibiting the formation of LPS-induced TNFα but showing no cytotoxic activity, so it can be used for the preparation of anti-inflammatory drug or act as a precursor of anti-inflammatory drugs, for the treatment of multiple inflammations. Therefore, the invention provides a new candidate compound for the development of anti-inflammatory drugs, and is of great significance for developing Chinese marine drug resources.


Find Patent Forward Citations

Loading…