The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2017

Filed:

Mar. 25, 2013
Applicant:

Hoffmann-la Roche Inc., Little Falls, NJ (US);

Inventors:

Norbert Oranth, Voerstetten, DE;

Nadine Losleben, Mannheim, DE;

Sascha Lutz, Neustadt, DE;

Adelbert Grossmann, Eglfing, DE;

Assignee:

Hoffmann-La Roche Inc., Little Falls, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 61/14 (2006.01); B01D 61/20 (2006.01); B01D 63/08 (2006.01); B01D 61/18 (2006.01); B01D 61/22 (2006.01);
U.S. Cl.
CPC ...
B01D 61/20 (2013.01); B01D 61/145 (2013.01); B01D 61/18 (2013.01); B01D 61/22 (2013.01); B01D 63/088 (2013.01); B01D 2313/243 (2013.01); B01D 2313/90 (2013.01); B01D 2315/10 (2013.01);
Abstract

A flow filtration system () for concentration of components contained in a fluid sample comprises a fluid channel () being formed by two conduits () allowing a bidirectional flow of the fluid sample through the fluid channel (), a tangential flow filtration module () and at least two pairs () of piston pumps () each having two piston pumps (), wherein the piston pumps () having a piston swept volume forming a reservoir being able to contain the fluid for volumes of up to 100 ml. The tangential flow filtration module () is located in the fluid channel () so that a fluid flowing through the channel () passes through the filtration module (). At each end () of the channel () one piston pump () of each pair () of piston pumps () is located in such a manner that the piston pumps are fluidically connected in parallel. The system () is arranged and adapted such that during the concentration process at least for a predetermined period of time only one of the pairs () of piston pumps () is used to drive the fluid through the tangential flow filtration module ().


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