The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2017

Filed:

Feb. 23, 2015
Applicant:

Glycovaxyn Ag, Schlieren, CH;

Inventors:

Michael T. Kowarik, Zurich, CH;

Michael L. Wetter, Zurich, CH;

Stefan J. Kemmler, Zurich, CH;

Micha A. Häuptle, Zurich, CH;

Veronica Gambillara, Meilen, CH;

Manuela Mally, Watt, CH;

Assignee:

GLYCOVAXYN AG, Schlieren, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01); A61K 39/108 (2006.01); C07K 14/21 (2006.01); A61K 39/02 (2006.01); C08B 37/00 (2006.01); A61K 39/00 (2006.01); C07K 14/245 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0258 (2013.01); A61K 39/02 (2013.01); A61K 47/4833 (2013.01); C07K 14/21 (2013.01); C08B 37/0063 (2013.01); C08B 37/0066 (2013.01); A61K 2039/55583 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/6087 (2013.01); A61K 2039/70 (2013.01); C07K 14/245 (2013.01);
Abstract

Provided herein is a novelO polysaccharide, O25B. Also provided herein are prokaryotic host cells comprising enzymes (e.g., glycosyltransferases) used in O25B production. The host cells provided herein produce O25B bioconjugates, wherein said bioconjugates comprise O25B linked to a carrier protein. Further provided herein are compositions, e.g., pharmaceutical compositions, comprising O25B and/or bioconjugates comprising O25B. Such compositions can be used as vaccines against infection with ExPEC, and may further comprise one or more additional bioconjugates.


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