The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2017

Filed:

Mar. 18, 2014
Applicant:

University of Florida Research Foundation, Incorporated, Gainesville, FL (US);

Inventors:

Joseph Larkin, Gainesville, FL (US);

Mark A. Atkinson, Gainesville, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 38/02 (2006.01); A61K 38/08 (2006.01); A61K 35/15 (2015.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); A61K 39/08 (2006.01); A61K 39/09 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/02 (2013.01); A61K 35/15 (2013.01); A61K 39/0008 (2013.01); A61K 39/0208 (2013.01); A61K 39/08 (2013.01); A61K 39/09 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/577 (2013.01); A61K 2039/58 (2013.01);
Abstract

The invention provides compositions for treating or preventing T1D (T1D), the compositions comprising one or more antigen presenting cells (APC) that have been pulsed with one or more bacteria and/or components of the bacteria, wherein the bacteria or their components confer upon the APCs the ability to inhibit the generation of diabetes-promoting T cells. The subject invention also provides a method of treating or preventing T1D in a subject, the method comprising administering APC that have been pulsed with one or more bacteria and/or components of the bacteria and wherein the bacteria or their components confer upon the APCs the ability to inhibit the generation of diabetes-promoting T cells.


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