The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2017

Filed:

May. 30, 2013
Applicant:

University of Medicine and Dentistry of New Jersey, Somerset, NJ (US);

Inventors:

Paola Leone, Cherry Hill, NJ (US);

Jeremy Francis, Cherry Hill, NJ (US);

Assignee:

Rowan University, Glassboro, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/50 (2006.01); C12N 15/86 (2006.01); A61K 38/52 (2006.01); A61K 35/30 (2015.01);
U.S. Cl.
CPC ...
A61K 38/50 (2013.01); A61K 35/30 (2013.01); A61K 38/52 (2013.01); C12N 15/86 (2013.01); C12Y 305/01015 (2013.01); C12N 2750/14141 (2013.01);
Abstract

The present invention provides a novel method of treatment for treating brain disorders that manifest oxidative stress by providing targeted populations of neurons with the ability to catabolize the acetylated amino acid derivative, N-acetylaspatic acid (NAA) and further supply extraphysiological levels of ATP to neurons via the targeted expression of the NAA catabolic enzyme aspartoacylase (ASPA) in neurons and astrocytes.


Find Patent Forward Citations

Leone, Paola. (2017). Metabolic therapy for oxidative stress in the brain through targeted neuronal catabolism of n-acetyl-aspartic acid (U.S. Patent No. 9700604). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9700604

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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