The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2017
Filed:
Apr. 08, 2015
Applicant:
Phasebio Pharmaceuticals, Inc., Malvern, PA (US);
Inventors:
Homayoun Sadeghi, Hillsborough, NC (US);
Suzanne Dagher, Raleigh, NC (US);
Andrew Turner, Durham, NC (US);
Assignee:
PHASEBIO PHARMACEUTICALS, INC., Malvern, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/22 (2006.01); A61K 38/39 (2006.01);
U.S. Cl.
CPC ...
A61K 38/2278 (2013.01); A61K 38/39 (2013.01);
Abstract
The present invention provides modified Vasoactive Intestinal Peptides (VIPs), encoding polynucleotides and vectors, as well as pharmaceutical compositions comprising the same. The invention further provides methods of making and using the modified VIP agents. In accordance with the invention the VIP exhibits an extended circulatory half-life, receptor-binding or biological potency, and/or altered receptor binding profile with respect to unmodified VIP.