The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2017
Filed:
Mar. 01, 2012
Applicants:
Stanley T. Carmichael, Sherman Oaks, CA (US);
Andrew N. Clarkson, Dunedin, NZ;
Inventors:
Stanley T. Carmichael, Sherman Oaks, CA (US);
Andrew N. Clarkson, Dunedin, NZ;
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 31/728 (2006.01); A61K 31/737 (2006.01); A61K 9/00 (2006.01); A61K 9/06 (2006.01); A61K 47/36 (2006.01); A61K 47/42 (2017.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); A61L 27/54 (2006.01); A61K 31/40 (2006.01); A61K 31/445 (2006.01); A61K 31/727 (2006.01);
U.S. Cl.
CPC ...
A61K 38/185 (2013.01); A61K 9/0085 (2013.01); A61K 9/06 (2013.01); A61K 31/40 (2013.01); A61K 31/445 (2013.01); A61K 31/727 (2013.01); A61K 31/728 (2013.01); A61K 31/737 (2013.01); A61K 38/18 (2013.01); A61K 47/36 (2013.01); A61K 47/42 (2013.01); A61L 27/3834 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 2300/414 (2013.01); A61L 2300/602 (2013.01); A61L 2300/64 (2013.01); A61L 2430/20 (2013.01);
Abstract
Methods of improving recovery of a mammal after an ischemic event (e.g., stroke) are provided. In various embodiments the methods involve administering a neural growth factor (e.g., BDNF) into the infarct (e.g., stroke) cavity in a biocompatible hydrogel formulation. In certain embodiments the hydrogel comprises a thiolated hyaluronan and a thiolated gelatin with an optional thiolated heparin.