The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 2017
Filed:
Aug. 13, 2015
Applicant:
Aziende Chimiche Riunite Angelini Francesco A.c.r.a.f. S.p.a., Rome, IT;
Inventors:
Maria Alessandra Alisi, Rome, IT;
Nicola Cazzolla, Rome, IT;
Barbara Garofalo, Rome, IT;
Guido Furlotti, Rome, IT;
Gabriele Magaro', Rome, IT;
Rosella Ombrato, San Lorenzo Del Vallo, IT;
Francesca Mancini, Rome, IT;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/5377 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 401/12 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/5377 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01);
Abstract
The present invention relates to the new use of 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta (GSK-3β) inhibitors and to their use in the treatment of GSK-3β-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; and (viii) epilepsies.