The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2017

Filed:

May. 14, 2013
Applicants:

Mochida Pharmaceutical Co., Ltd., Tokyo, JP;

Kyushu University, National University Corporation, Fukuoka-shi, Fukuoka, JP;

Inventors:

Yutaka Kiyohara, Fukuoka, JP;

Toshiharu Ninomiya, Fukuoka, JP;

Takashi Yano, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/232 (2006.01); A61K 31/202 (2006.01); G01N 33/68 (2006.01); G01N 33/92 (2006.01); G01N 30/88 (2006.01);
U.S. Cl.
CPC ...
A61K 31/232 (2013.01); A61K 31/202 (2013.01); G01N 33/6893 (2013.01); G01N 33/92 (2013.01); G01N 2030/8813 (2013.01); G01N 2333/4737 (2013.01); G01N 2800/2871 (2013.01); G01N 2800/32 (2013.01); G01N 2800/324 (2013.01); G01N 2800/325 (2013.01);
Abstract

The present invention provides the following: a cardiovascular disease primary prevention agent, which comprises as the active ingredient at least one selected from the group consisting of EPA, salts thereof, and esters thereof and is for lowering the risk of cardiovascular disease by administration to subjects having a blood (serum or plasma) hs-CRP level of 1.0 mg/L or higher in spite of no history of cardiovascular disease; a combination marker comprising the blood hs-CRP value and serum EPA/AA ratio for evaluating the primary risk of cardiovascular disease in subjects having no history of cardiovascular disease; and a method for extracting subjects with high risk of cardiovascular disease and/or a method for preventing cardiovascular disease.


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