The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 11, 2017

Filed:

Aug. 02, 2013
Applicant:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Inventors:

Arnulf Staib, Heppenheim, DE;

Reinhold Mischler, Ludwigshafen, DE;

Martin Hajnsek, Graz, AT;

Harvey Buck, Indianapolis, IN (US);

Walter Jernigan, Carmel, IN (US);

Assignee:

Roche Diabetes Care, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/05 (2006.01); A61B 5/1486 (2006.01); A61B 5/145 (2006.01);
U.S. Cl.
CPC ...
A61B 5/14865 (2013.01); A61B 5/14532 (2013.01);
Abstract

An in vivo amperometric sensor is provided for measuring the concentration of an analyte in a body fluid. The sensor comprises a counter electrode and a working electrode, and the working electrode comprises a sensing layer which is generally water permeable and arranged on a support member adjacent to a contact pad. The sensing layer comprises an immobilized enzyme capable of acting catalytically in the presence of the analyte to cause an electrical signal. The sensing layer has an upper surface facing the body fluid and a lower surface facing away from the body fluid, and the immobilized enzyme is distributed within the sensing layer in such a way that the enzyme concentration in the middle between the upper and lower surfaces is at least as high as on the upper surface of the sensing layer.


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