The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
Jan. 14, 2016
National University Corporation Okayama University, Okayama-shi, Okayama, JP;
Kosuke Kuroda, Okayama, JP;
Hiroshi Morimatsu, Okayama, JP;
Hidenori Wake, Okayama, JP;
Shuji Mori, Okayama, JP;
Masahiro Nishibori, Okayama, JP;
Hideo Takahashi, Okayama, JP;
Keyue Liu, Okayama, JP;
Kiyoshi Teshigawara, Okayama, JP;
Masakiyo Sakaguchi, Okayama, JP;
National University Corporation Okayama University, Okayama, JP;
Abstract
The present invention provides a neutrophil activation regulator comprising a histidine-rich glycoprotein (HRG) for the treatment of systemic inflammatory response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation in a subject in need thereof. Further, the present invention provides methods for predicting the severity of systemic inflammatory response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation in a subject in need thereof, and methods for predicting the survival of a subject with systemic inflammatory response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation, that comprise determining the blood level of histidine-rich glycoprotein in the subject.