The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2017

Filed:

Dec. 17, 2015
Applicant:

Epitomics, Inc., Cambridge, GB;

Inventor:

Guo-Liang Yu, Hillsborough, CA (US);

Assignee:

EPITOMICS, INC., Burlingame, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); G01N 33/53 (2006.01); G01N 33/577 (2006.01); C07K 16/28 (2006.01); G01N 33/68 (2006.01); G01N 33/566 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/577 (2013.01); C07K 16/00 (2013.01); C07K 16/2863 (2013.01); C12Q 1/6876 (2013.01); G01N 33/566 (2013.01); G01N 33/6854 (2013.01); C07K 2317/10 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01);
Abstract

In certain embodiments, the method may comprise: a) obtaining the antibody sequences from a population of B cells; b) grouping the antibody sequences to provide a plurality of groups of lineage-related antibodies; c) testing a single antibody from each of the groups in a bioassay and, after the first antibody has been identified, d) testing further antibodies that are in the same group as the first antibody in a second bioassay. In another embodiment, the method may comprise: a) testing a plurality of antibodies obtained from a first portion of an antibody producing organ of an animal; b) obtaining the sequence of a first identified antibody; c) obtaining from a second portion of said antibody producing organ the sequences of further antibodies that are related by lineage to said first antibody; and, c) testing the further antibodies in a second bioassay.


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