The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2017

Filed:

Nov. 13, 2012
Applicants:

The Regents of the University of California, Oakland, CA (US);

Brigham Young University, Provo, UT (US);

Inventors:

William Dunbar, Santa Cruz, CA (US);

Holger Schmidt, Santa Cruz, CA (US);

Aaron Hawkins, Provo, UT (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); G01N 27/447 (2006.01); G01N 33/487 (2006.01); C12Q 1/68 (2006.01); B82Y 15/00 (2011.01);
U.S. Cl.
CPC ...
G01N 27/44791 (2013.01); C12Q 1/6869 (2013.01); G01N 33/48721 (2013.01); B82Y 15/00 (2013.01);
Abstract

Provided is a device comprising a channel through and defined by a plurality of layers surrounding the channel, the channel connecting a first and a second chambers separated by the plurality of layers, wherein the plurality of layers comprise a first layer, a second layer; and a conductive middle layer disposed between the first and second layers, wherein the channel comprises (a) a first region defined by the first layer, denoted as an inlet, that is about 0.5 nm to about 100 nm in diameter and (b) a second region defined by the second layer, denoted as an outlet, wherein the inlet and the outlet are about 10 nm to about 1000 nm apart from each other, and wherein the first and second chambers and the middle layer are connected to a power supply. Also provided are methods of preparing and using the device, in particular for nucleic acid sequencing.


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