The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
Dec. 25, 2013
Applicants:
Biocomo, Inc., Mie, JP;
Mie University, Mie, JP;
Inventors:
Masayuki Fukumura, Mie, JP;
Junpei Ohtsuka, Mie, JP;
Tetsuya Nosaka, Mie, JP;
Masato Tsurudome, Mie, JP;
Mitsuo Kawano, Mie, JP;
Ken-ichiro Hara, Mie, JP;
Assignees:
BIOCOMO INC., Mie, JP;
MIE UNIVERSITY, Mie, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/00 (2006.01); C12N 15/86 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01); A61K 39/145 (2006.01); C12N 15/09 (2006.01); A61K 39/12 (2006.01); A61K 39/155 (2006.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); A61K 39/0011 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/155 (2013.01); C12N 7/00 (2013.01); C12N 15/09 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5256 (2013.01); C07K 2319/00 (2013.01); C12N 2760/16034 (2013.01); C12N 2760/18734 (2013.01); C12N 2760/18743 (2013.01); C12N 2760/18762 (2013.01); C12N 2760/18763 (2013.01);
Abstract
Disclosed are: a virus vector in which a gene encoding an antigenic polypeptide is integrated in human parainfluenza virus type 2 gene, wherein the antigenic polypeptide is expressed in the form of a fusion protein with a viral structural protein; and a method for producing the same. The virus vector of the present invention contains a quantitatively large amount of the antigenic peptide on the virus particle and can efficiently deliver the antigenic polypeptide to a target cell.