The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
Jul. 18, 2013
Applicant:
Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);
Inventors:
Thomas Battersby, El Cerrito, CA (US);
Adrian Nielsen Fehr, San Francisco, CA (US);
Minxue Zheng, Foster City, CA (US);
Assignee:
Siemens Healthcare Diagnostics Inc., Tarrytown, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1065 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6837 (2013.01); C12Q 1/6874 (2013.01);
Abstract
The present disclosure relates to normalization of biological samples, particularly samples comprising nucleic acids to be sequenced. The normalization protocols described herein may be utilized across multiple samples to cap total stoichiometric input and minimize variations in transcript abundance on a per-sample basis in a multiplexed fashion to dramatically increase the accuracy, capacity and efficiency of nucleic acid sequencing.