The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
May. 20, 2015
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Patrick Sean Daugherty, Santa Barbara, CA (US);
Jeffrey Rice, Goleta, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C07K 14/19 (2006.01); C07K 14/195 (2006.01); C12N 15/00 (2006.01); C07K 14/245 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1037 (2013.01); C07K 14/195 (2013.01); C07K 14/245 (2013.01); C12N 15/00 (2013.01); C07K 2319/00 (2013.01);
Abstract
Methods of making and using bacterial display polypeptide libraries using circularly permuted OmpX (CPX) variants are disclosed. The invention further relates to methods for enhancing the display of proteins and peptides at the surface of bacteria by optimizing linkers and incorporating mutations at positions 165 and 166 of CPX.