The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2017

Filed:

Sep. 10, 2012
Applicants:

Paul J. Maddon, Scarsdale, NY (US);

Gerald P. Donovan, York, ME (US);

William C. Olson, Yorktown Heights, NY (US);

Norbert Schuelke, East Walpole, MA (US);

Jason Gardner, Wellesley, MA (US);

Dangshe MA, Millwood, NY (US);

Inventors:

Paul J. Maddon, Scarsdale, NY (US);

Gerald P. Donovan, York, ME (US);

William C. Olson, Yorktown Heights, NY (US);

Norbert Schuelke, East Walpole, MA (US);

Jason Gardner, Wellesley, MA (US);

Dangshe Ma, Millwood, NY (US);

Assignee:

PSMA Development Company, LLC, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/40 (2006.01); A61K 38/17 (2006.01); A61K 47/48 (2006.01); A61K 51/10 (2006.01); C07K 14/47 (2006.01); C07K 16/30 (2006.01); G01N 33/574 (2006.01); A61K 39/395 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 38/1709 (2013.01); A61K 39/0011 (2013.01); A61K 47/48469 (2013.01); A61K 47/48638 (2013.01); A61K 51/1072 (2013.01); A61K 51/1093 (2013.01); A61K 51/1096 (2013.01); C07K 14/4748 (2013.01); C07K 16/3069 (2013.01); G01N 33/57434 (2013.01); A61K 39/39558 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01);
Abstract

The invention includes stable multimeric, particularly dimeric, forms of PSMA protein, compositions and kits containing dimeric PSMA protein as well as methods of producing, purifying and using these compositions. Such methods include methods for eliciting or enhancing an immune response to cells expressing PSMA, including methods of producing antibodies to dimeric PSMA, as well as methods of treating cancer, such as prostate cancer.


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