The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
Oct. 24, 2013
Applicant:
Fraunhofer-gesellschaft Zur Förderung Der Angewandten Forschung E.v., Munich, DE;
Inventors:
Stefan Barth, Munich, DE;
Theopilus Thepen, Munich, DE;
Dmitrij Hristodorov, Aachen, DE;
Radoslav Mladenov, Aachen, DE;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 15/00 (2006.01); C07H 21/04 (2006.01); C12P 21/08 (2006.01); C07K 16/00 (2006.01); C07K 16/28 (2006.01); C07K 14/52 (2006.01); C07K 14/54 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 16/283 (2013.01); C07K 14/47 (2013.01); C07K 14/521 (2013.01); C07K 14/54 (2013.01); C07K 16/2878 (2013.01); C07K 16/2896 (2013.01); C07K 2317/622 (2013.01); C07K 2319/21 (2013.01); C07K 2319/33 (2013.01);
Abstract
A compound formed from at least one component A comprising a binding domain for extra-cellular surface structures of a diseased proliferating cell that internalized upon binding of component A of said compound, and at least one component B, characterized in that component B is a polypeptide which amino acid sequence comprises a microtubule-associated protein (MAP) or comprises at least a partial sequence of the MAP, the partial sequence having maintained the binding function of the MAP to a microtubule.