The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
Dec. 27, 2015
Inje University Industry-academic Cooperation Foundation, Gyeongsangnam-do, KR;
INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, Gimhae-si, Gyeongsangnam-Do, KR;
Abstract
A pharmaceutical composition for preventing or treating an ocular surface disease is disclosed, wherein the pharmaceutical composition includes, as an active component, collagen type II α1 based peptide SEQ ID NO: 2 isolated from chondrocyte-derived extracellular matrix (CDEM). In an alkaline burn animal mode treated with peptide SEQ ID NO: 2, the occurrence of corneal opacification is reduced as well as the expression of angiogenic factors. In addition, the expression of inflammatory markers is reduced while the expression of inflammation-inducing factor is suppressed. The peptide SEQ ID NO: 2 may be applied to a pharmaceutical composition for preventing or treating an ocular surface disease.