The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2017

Filed:

Dec. 15, 2015
Applicant:

Soonchunhyang University Industry Academy Cooperation Foundation, Chungcheongnam-do, KR;

Inventor:

Jungkyun Im, Chungcheongnam-do, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/00 (2006.01); C07H 19/10 (2006.01); C07H 1/02 (2006.01); C07H 19/06 (2006.01); C07H 1/04 (2006.01); C07H 19/067 (2006.01);
U.S. Cl.
CPC ...
C07H 19/10 (2013.01); C07H 1/02 (2013.01); C07H 1/04 (2013.01); C07H 19/06 (2013.01); C07H 19/067 (2013.01);
Abstract

A novel C1-phosphate log of uridine-5'-diphosphate (UDP)-GlcNAc as an effective OGT (O-linked N-acetylglucosamine (O-GlcNAc) transferase) inhibitor, and a preparation method for the same provides a compound having an OGT inhibitory effect that can be used as a useful tool in the studies on various vital phenomena in association with the protein modification by O-GlcNAc within cells and furthermore as a candidate substance in the treatment or research of diseases related to the protein modification by O-GlcNAc, such as cancers, diabetes, or degenerative neurological diseases.


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