The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2017

Filed:

Dec. 16, 2013
Applicants:

Cameron James Smith, Lawrenceville, NJ (US);

Edward Sherer, Manville, NJ (US);

Louis-charles Campeau, Morris Plains, NJ (US);

James Balkovec, Martinsville, NJ (US);

William John Greenlee, Teaneck, NJ (US);

Derun LI, Scotch Plains, NJ (US);

Liangqin Guo, Edison, NJ (US);

Tin-yau Chan, Edison, NJ (US);

Yi-heng Chen, Whippany, NJ (US);

Yili Chen, Hillsborough, NJ (US);

Samuel Chackalamannil, Califon, NJ (US);

John Qiang Tan, Westfield, NJ (US);

Tomokazu Hirabayashi, Shizuoka Prefecture, JP;

Mika Sekioka, Shizuoka Prefecture, JP;

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Mochida Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Cameron James Smith, Lawrenceville, NJ (US);

Edward Sherer, Manville, NJ (US);

Louis-Charles Campeau, Morris Plains, NJ (US);

James Balkovec, Martinsville, NJ (US);

William John Greenlee, Teaneck, NJ (US);

Derun Li, Scotch Plains, NJ (US);

Liangqin Guo, Edison, NJ (US);

Tin-Yau Chan, Edison, NJ (US);

Yi-Heng Chen, Whippany, NJ (US);

Yili Chen, Hillsborough, NJ (US);

Samuel Chackalamannil, Califon, NJ (US);

John Qiang Tan, Westfield, NJ (US);

Tomokazu Hirabayashi, Shizuoka Prefecture, JP;

Mika Sekioka, Shizuoka Prefecture, JP;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); C07D 417/06 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01); C07D 413/12 (2006.01); C07D 471/04 (2006.01); C07D 413/06 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); C07D 413/06 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/06 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01);
Abstract

The present invention provides a compound of Formula (I) where A is a heterocycle ring system and B is a heterocycle ring system or aryl ring system, and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes.


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