The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
Jun. 19, 2015
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Kristos Adrian Moshos, Belmont, MA (US);
Valdas Jurkauskas, Cambridge, MA (US);
Manuel Scanu, Milan, IT;
Michele Benotti, Pavia, IT;
Assignee:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 501/04 (2006.01); C07D 285/08 (2006.01);
U.S. Cl.
CPC ...
C07D 501/04 (2013.01); C07D 285/08 (2013.01);
Abstract
This disclosure relates to an improved synthesis of cephalosporin antibiotic compounds such as ceftolozane, and compositions and methods of use thereof. Thiadiazolyl-oximinoacetic acid compounds such as TATD can be reacted to yield the activated thiadiazolyl-oximinoacetic acid methanesulfonate ester compounds useful in the manufacture of cephalosporin antibiotic compounds.