The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2017

Filed:

Jan. 15, 2016
Applicant:

Procell Therapeutics Inc., Seoul, KR;

Inventors:

Ki Deok Shin, Daejeon, KR;

Kang Jin Lee, Seoul, KR;

Sunny Lim, Gyeonggi-do, KR;

Byung Kyu Lee, Gyeonggi-do, KR;

Jong Rae Kim, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/08 (2006.01); A61K 38/10 (2006.01); A61K 47/48 (2006.01); A61K 31/192 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); A61K 8/64 (2006.01); A61Q 19/08 (2006.01); C12N 15/113 (2010.01); A61K 8/365 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 8/365 (2013.01); A61K 8/64 (2013.01); A61K 31/192 (2013.01); A61Q 19/08 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C12N 15/113 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3513 (2013.01); C12N 2320/32 (2013.01);
Abstract

The present invention relates to an improved macromolecule transduction domain (MTD), which facilitates permeating the cell membrane of a biologically active molecule, having enhanced cell permeability. Specifically, an improved MTD according to the present invention, compared to an existing MTD, can transmit various types of biologically active molecule from inside the body and inside a test tube more effectively, and thus can be effectively used in a method to genetically alter a biologically active molecule so as to have cell permeability or in a method to transport a biologically active molecule into a cell, or the like. Additionally, the improved MTD can be very useful in development of new drugs and incrementally modified drugs as uses of the improved MTD are possible in drug delivery systems, recombinant protein vaccines or DNA/RNA therapeutic agents, gene or protein therapies, and pharmacologically or medically useful protein production or medical, pharmacological and pharmaceutical compositions.


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