The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
Jul. 16, 2013
Applicant:
Amicus Therapeutics, Inc, Cranbury, NJ (US);
Inventors:
Richie Khanna, Piscataway, NJ (US);
Kenneth Joseph Valenzano, East Brunswick, NJ (US);
Susan Elizabeth Fowles, Ware, GB;
Assignee:
AMICUS THERAPEUTICS, INC., Cranbury, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/47 (2006.01); C12N 9/40 (2006.01); A61K 31/445 (2006.01);
U.S. Cl.
CPC ...
A61K 38/47 (2013.01); A61K 31/445 (2013.01); C12N 9/2465 (2013.01); C12Y 302/01022 (2013.01);
Abstract
The present application provides for compositions comprising α-galactosidase A in combination with an active site-specific chaperone for the α-galactosidase A, and methods for treating Fabry disease in a subject in need thereof, that includes a method of administering to the subject such compositions. The present application also provides methods for increasing the in vitro and in vivo stability of an α-galactosidase A enzyme formulation.