The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2017
Filed:
Jun. 08, 2016
Applicant:
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Inventors:
Assignee:
Otsuka Pharmaceutical Co., Ltd., Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/501 (2006.01); A61K 31/34 (2006.01); A61K 31/135 (2006.01); A61K 31/15 (2006.01); A61K 31/165 (2006.01); A61K 31/343 (2006.01); A61K 31/381 (2006.01); A61K 31/4525 (2006.01); A61K 31/137 (2006.01); A61K 31/138 (2006.01);
U.S. Cl.
CPC ...
A61K 31/496 (2013.01); A61K 31/135 (2013.01); A61K 31/137 (2013.01); A61K 31/138 (2013.01); A61K 31/15 (2013.01); A61K 31/165 (2013.01); A61K 31/343 (2013.01); A61K 31/381 (2013.01); A61K 31/4525 (2013.01);
Abstract
The pharmaceutical composition of the present invention comprises () a carbostyril derivative and () a serotonin reuptake inhibitor in a pharmaceutically acceptable carrier. The carbostyril derivative may be aripiprazole or a metabolite thereof, which is a dopamine-serotonin system stabilizer. The serotonin reuptake inhibitor may be fluoxetine, duloxetine, venlafaxine, milnacipran, citalopram, fluvoxamine, paroxetine, sertraline or escitalopram. The pharmaceutical composition of the present invention is useful for treating patients with mood disorders, particularly depression or major depressive disorder.