The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2017

Filed:

Apr. 16, 2015
Applicant:

Celgene Corporation, Summit, NJ (US);

Inventors:

Kyle J. MacBeth, San Francisco, CA (US);

Aaron N. Nguyen, San Jose, CA (US);

Jorge Dimartino, Belmont, CA (US);

Assignee:

Celgene Corporation, Summit, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61K 31/282 (2006.01); A61K 31/706 (2006.01); A61K 31/7052 (2006.01); A61K 31/7042 (2006.01); A61K 31/337 (2006.01); A61K 31/7068 (2006.01); A61K 45/06 (2006.01); A61K 47/48 (2006.01); A61K 31/7064 (2006.01);
U.S. Cl.
CPC ...
A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/706 (2013.01); A61K 31/7042 (2013.01); A61K 31/7052 (2013.01); A61K 31/7068 (2013.01); A61K 45/06 (2013.01); A61K 47/48284 (2013.01); A61K 31/7064 (2013.01);
Abstract

Provided herein are methods for treating subjects having a cancer, such as a relapsed or refractory solid tumor, wherein the method comprises administering to the subject a cytidine analog. In certain of the methods, the cytidine analog is administered alone or in combination with one or more anti-cancer agents. Also provided are methods for using a cytidine analog, to treat diseases and disorders including disorders related to abnormal cell proliferation, hematologic disorders, and immune disorders, among others. In certain of the methods, the cytidine analog is formulated in an oral dosage form and administered orally.


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