The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 2017

Filed:

Sep. 07, 2005
Applicants:

Joseph T. Persyn, Lakehills, TX (US);

Joseph A. Mcdonough, Helotes, TX (US);

Neal K. Vail, San Antonio, TX (US);

Darren E. Barlow, Floresville, TX (US);

Albert M. Zwiener, San Antonio, TX (US);

Eliot M. Slovin, Arlington, TX (US);

Inventors:

Joseph T. Persyn, Lakehills, TX (US);

Joseph A. McDonough, Helotes, TX (US);

Neal K. Vail, San Antonio, TX (US);

Darren E. Barlow, Floresville, TX (US);

Albert M. Zwiener, San Antonio, TX (US);

Eliot M. Slovin, Arlington, TX (US);

Assignee:

SOUTHWEST RESEARCH INSTITUTE, San Antonio, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 9/16 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5089 (2013.01); A61K 9/0048 (2013.01); A61K 9/1694 (2013.01);
Abstract

This invention is directed to an apparatus and method for producing microparticles comprising pharmacologically active agents and biodegradable polymers. The apparatus includes a spinning disk containing a reservoir in the center thereof and a flat inclined surface. The apparatus optionally includes serrations and/or a flat surface beneath the periphery of the disk that is parallel to the rotational axis of the disk. The invention is also directed to a method for producing microparticles containing pharmacologically active agents, using the spinning disk apparatus. Formulations containing ophthalmically active agents are provided. Formulations exhibiting zero order release rates are also described.


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